The native distribution of blood flower or Mexican butterfly weed is not known. Wyatt and Broyles, in their June 1997 paper, “The Weedy Tropical Milkweeds Asclepias curassavica and A. fruticosa are Self-Compatible” (Biotropica, Vol. 29, No. 2, pp. 232-234) cite a 1954 reference (Woodson) that conjectures South America as the native range for this species, but allows that Central America, the Antilles or Mexico are also possibilities. The modern day extent of the species covers much of the subtropics and tropics of both the Old World and New World. Despite an unknown native origin, its name reflects the place where the first specimens were likely collected, Curaçao.
In temperate-region gardens and homes of the world, it is suggested as both an excellent annual planting (Kemper Center for Home Gardening Plant of Merit) or greenhouse plant (Cal’s Plant of the Week).
CalPhotos has more photographs of Asclepias curassavica.